Citicoline: pharmacological and clinical review, 2010 update

نویسنده

  • Julio J. Secades
چکیده

Introduction S1 Pharmacological actions S2 Traumatic lesions and experimental cerebral oedema S2 Cerebral hypoxia and ischaemia S5 Synaptic transmission and neurotransmitter levels S13 Learning performance, memory and brain ageing S17 Experimental withdrawal syndrome and intoxications S19 Toxicity S20 Acute toxicity S20 Subacute toxicity S20 Chronic toxicity S20 Teratogenicity S20 Pharmacokinetics S21 Plasma level curves. Bioavailability S21 Tissue difussion and distribution. Transport and metabolism S21 Elimination route and kinetics S23 Clinical experience S23 Head injury and sequelae S23 Acute cerebrovascular disease and sequelae S28 Cognitive disorders S37 Other clinical experiences S43 Safety S45

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تاریخ انتشار 2011